Polo-like kinase 4 shapes up.
نویسندگان
چکیده
Polo-like kinase 4 (Plk4) is a master regulator of centriole duplication and targets to centrioles through the association of its cryptic polo box domain with centriole receptors. In this issue of Structure, Shimanovskaya and colleagues unveil a new dimeric architecture of Plk4's cryptic polo box that reveals a conserved mechanism for centriole targeting of the kinase.
منابع مشابه
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ورودعنوان ژورنال:
- Structure
دوره 22 8 شماره
صفحات -
تاریخ انتشار 2014